Bone Abstracts

The effects of dexamethasone on trabecular and cortical bone in OPG−/− mice were investigated in present study. Forty 6-month-old C57BL/6J female mice, including wt (n=20) and OPG knockout (OPG−/−, n=20), were randomdly divided into four groups and treated with either sterile normal saline or dexamethasone at 1 mg/kg by intramuscular injection 3 days per week. All mice were sacrificed at 4 weeks after these treatm...